Endocrine Abstracts

Introduction: The aim of this study was to investigate the characteristics of glucocorticoid-induced diabetes (GCID) in 18 non-diabetic patients before the initiation of corticosteroid therapy.Patients and Methods: It is a retrospective study including non-diabetic hospitalized patients who developed diabetes after initiation of corticosteroid therapy.Results: Eighteen patients (5 males/13 females) with a mean age of 59.5 years wer...

Introduction: Thyroid pathology is common in women of reproductive age. Evaluation of thyroid function is classically recommended in cases of recurrent abortion. The presence of dysthyroidism or antithyroid antibodies increases the risk of abortion. We report two observations of hypofertility related to thyroid pathology and discuss the therapeutic course.Case 1: A 33 year old woman was referred for etiological investigation of recurrent abortion. She pr...

IntroductionType 3 autoimmune polyendocrine syndrome (APS-3) is defined by the presence of an autoimmune thyroid disease and another autoimmune illness, excluding Addison’s disease; this is a frequent combination. Graves’ disease (GD) is an autoimmune disorder affecting approximately 0.5% of general population. It’s occurrence in autoimmune polyendocrine syndrome (APS) is less common than Hashimoto thyroiditis. The aim of our study was to ...

IntroductionAutoimmune Polyendocrine Syndrome (APS) is defined by the presence of 2 or more autoimmune induced endocrine failures in a single patient. There are 4 types of APS: type1 including chronic muco-cutaneous candidiasis, hypoparathyroidism, Addison disease (AD) and ectodermal dystrophy, APS type 2 and 3 containing autoimmune thyroide disease (AITD), type1 diabetes (DT1) with (type2) or without adrenal failure (type3) and type 4 not falling into t...

IntroductionVasculitis with antineutrophilic cytoplasmic antibodies (ANCA) has been reported in patients treated with anti-thyroid drugs, especially Propylthiouracil and exceptionally with benzylthiouracil (BTU). We present here a case of ANCA-anti-MPO-associated vasculitis related to BTU.Case presentationA 46 old women was treated with BTU during 18 months for Basedow’s...

Introduction: Hashimoto’s encephalopathy (HE) is characterised by the combination of clinical signs of encephalitis and autoimmune thyroiditis with elevated levels of antithyroid antibodies (ATA). It is a rare condition and its etiopathogenesis is still poorly understood.Observation: we present a 33-year-old female patient who was hospitalized for gait disorders. The diagnosis of a chronic cerebellar syndrome related to Hashimoto’s encephalitis...

Introduction: Hypothyroidism is a consequence of thyroid hormone deficiency which may be of peripheral or central origin. If hypothyroidism is left untreated, the symptoms progress and lead to life-threatening complications.Patients and method: Retrospective study of 67 patients with primary hypothyroidism. We determined the different complications associated with hypothyroidism.Results: We collected 67 patients with overt hypothyr...

Introduction: Autoimmune bullous dermatoses (ABD) represent a heterogeneous group of AIDs that target different epidermal or subepidermal proteins of the skin and/or mucous membranes. As with any autoimmune disease (AID), it may be associated with other AIDs. We report a case of ABD associated with Graves’ disease (GD).Observation: The ABD was a pemphigus vulgaris (PV) that was diagnosed at the age of 25 years in our patient and she was treated with...

Introduction: Alopecia is an autoimmune disease (AID) affecting the hair follicles. Alopecia can become generalised and affect all hairy areas (universal alopecia). As with any AID, it may be associated with other AIDs. We report 2 cases of the association of alopecia with autoimmune thyroid disease (AITD).Observation: The subjects were a man and a woman aged 48 and 54 years respectively. They presented with hypothyroidism. Hashimoto’s thyroiditis (...